Keyto PMMA Diffusion Bonded Manifold | Transparent Multi-Layer

Keyto's bonded manifold is made by molecular bonding of multi-layer processed parts with specific flow path features and supports up to five layers. It integrates functions such as sample addition, dilution, reagent mixing, reaction, separation, and detection, saving reagents and enhancing system integration. The manifold supports multi-level, multi-fluid path designs with material options including PMMA, PEI, and PVC, and offers O-type, square, and D-type flow path structures. Keyto's O-type structure provides large fluidity, low resistance, and minimal dead volume, supported by mature mass production capabilities.

Key Parameters:

Customized

Reference Model:

Manifold-PMMA

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Keyto PMMA Diffusion Bonded Manifold | Transparent Multi-Layer

Comparable Products

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Keyto PEI Diffusion Bonded Manifold | Repeatable Flow Control

Keyto PEI Diffusion Bonded Manifold | Integrated Workflow Manifold

Keyto PEI Diffusion Bonded Manifold | Tunable Channel Geometry

Keyto PEI Diffusion Bonded Manifold | Efficient Workflow Integration

Keyto PEI Diffusion Bonded Manifold | Flow Resistance Optimization | Reagent Saving

Comparison/Performance

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Overview

Keyto PMMA Diffusion Bonded Manifold

Transparent, multi-layer fluid routing for fast verification and stable performance.

Keyto’s PMMA diffusion bonded manifold is built by molecular-level bonding of precision-machined layers to create sealed, multi-path microfluidic networks. Designed for compact instruments, it supports up to five layers and enables reliable functions such as sample introduction, dilution, reagent mixing, reaction routing, separation, and detection. With transparent PMMA, engineers can visually inspect flow behavior during development and validation. Channel geometries can be customized (square, round, or D-shaped), and designs can be optimized for low dead volume and consistent flow resistance based on your 2D/3D drawings.

Feature Bullets

Diffusion-bonded multi-layer construction (up to 5 layers) for compact fluid routing
Transparent PMMA for visual verification and easier troubleshooting
Minimum channel feature down to 0.5 mm with ±0.01 mm channel tolerance (design dependent)
Square / round / D-shaped channel options to balance dead volume and flow resistance
Supports dilution, mixing, reaction routing, separation, and detection workflows
Custom design support: send 2D/3D CAD for DFM feedback and rapid prototyping

FAQ

Q1: Why choose PMMA for a bonded manifold?
A: PMMA offers high clarity for visual inspection, making it ideal for prototyping, optical-friendly setups, and development-stage validation.

Q2: What bonding methods do you support?
A: We support diffusion bonding, solvent bonding, laser bonding, and ultrasonic bonding—selected based on material and application needs.

Q3: What files should I provide for quotation and review?
A: 2D drawings (PDF/DXF) and/or 3D models (STEP/IGES) plus target media, temperature, and pressure conditions.

Q4: Can you optimize the design for low dead volume?
A: Yes. We can propose channel and cavity optimizations to reduce dead zones, stabilize flow, and improve consistency.

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